Typhoid Vaccination for Travel

The disease is caused by the bacteria Salmonella Typhi and Salmonella Paratyphi A, B or C. Typhoid is transmitted by food and drink that has been contaminated with human faeces or urine (faecal-oral route).

Typhoid can be found throughout the world but it is more common in countries where water or food supplies are liable to be contaminated with human excreta especially in Africa, the Indian Sub-continent, South East Asia and South America.

The risks for travelers

Consumption of food and drink that has been contaminated with faeces or urine from a human case or carrier; direct faecal oral contamination can also occur.

As with all other illnesses spread by the faecal oral route, precautionary measures should be taken to avoid consumption of potentially contaminated drinks and drinking water and to ensure food is uncontaminated or cooked thoroughly.

Personal hygiene when eating and drinking is also important including hand washing prior to eating and using clean plates, cups and utensils.

TYPHIM Vi vaccination

The TYPHIM Vi vaccination

Signs and symptoms of Typhoid


  • Fever
  • Constipation or sometimes diarrhoea
  • Abdominal pain, loss of appetite
  • Myalgia and headache
  • Faint pink ‘rose spot’ rash can occasionally be seen


  • Disseminated disease with multi organ involvement
  • Intestinal perforation
  • Meningitis

Typhoid Vaccination

Vaccination should be considered under the following circumstances and is dependent on the individual risk assessment

Vaccination is recommended for travellers to high risk areas where food and water may be contaminated.

Travel to low risk areas  – vaccination may be recommended only to those staying in conditions with poor sanitation and unable to maintain their own hygiene precautions e.g. hand hygiene and water purification.

Long term travellers staying for long periods.

A previous typhoid illness does not confer reliable immunity and, when indicated, vaccine should still be used.

Countries endemic for typhoid

Countries endemic for typhoid ®WHO 2009

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